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Habits and Hustle

Episode 575: Dr. Jonathan Schoeff: Peptides and the Marketing Behind Modern Longevity - Part 2

July 28, 2026·1h 42m

Are you chasing longevity hacks while missing the habits that actually change your health? Everyone wants the shortcut. The GLP-1. The fasting protocol. The supplement. The perfect biomarker. The next thing that promises better energy, better body composition, and a longer life. But the real issue is that most people are drowning in information and still missing what actually moves the needle. Your body is not random. Muscle affects insulin sensitivity. Movement changes how glucose gets used. Sleep impacts recovery. Fasting can be powerful when it is done strategically. And the right biomarkers can show you risks that "normal" lab work may completely miss. Once you understand the why behind the habit, you stop guessing and start making smarter decisions. In this episode of Habits and Hustle, I sit down with Dr. Jonathan Schoeff, surgeon, longevity expert, and co-founder of The Longevity Lab, to break down the real science behind GLP-1s, muscle loss, fasting, testosterone, grip strength, key biomarkers, movement, sleep, and what actually supports long-term health. What's Discussed: (1:26:03) Why GLP-1s are more nuanced than the muscle loss headlines suggest. (1:30:31) How strategic fasting can support fat loss without sacrificing muscle. (1:33:09) Why fasting activates repair pathways and metabolic flexibility. (1:39:26) What fasting actually does to insulin, ketosis, and fat burning. (1:42:29) Why random five-day fasts may not work the way people think. (1:55:24) How to structure a pre-fast, fast, and post-fast day. (1:57:02) Why walking after your last meal can change glucose and insulin response. (2:09:31) How metabolic dysfunction can drive low testosterone in men. (2:23:29) What biomarkers most doctors miss, including fasting insulin and lipoprotein(a). (2:31:23) Why grip strength is an overhyped longevity metric and what matters more.