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← Health vs Hype with the American Medical Association

Sea Moss, Leaky Gut and Probiotics: Separating Gut Health Facts from Hype

October 27, 2026·36m

Can probiotics, prebiotics, sea moss, and fermented foods really improve your gut health? And what does the science actually say about your gut microbiome? On this episode of Health vs. Hype from the American Medical Association, host Trace Dominguez explores the science behind gut health trends with Danielle Brown, holistic nutritionist and New York Times bestselling cookbook author behind Healthy Girl Kitchen, and Dr. Mohamed Mokadem, gastroenterologist and professor of medicine at the University of Iowa. From sea moss gel and probiotic supplements to postbiotics, prebiotics, fermented foods, and so-called “leaky gut,” we examine which wellness claims have scientific support and where the evidence is still developing. Dr. Mokadem explains what the gut microbiome does, how diet and antibiotics can affect it, and what researchers know about the gut-brain connection and its relationship to digestion, stress, and mental health. We also explore whether everyone needs a probiotic, how prebiotics differ from probiotics, what postbiotics actually are, and why there’s no single ideal microbiome for everyone. Plus, Danielle shares her personal journey with plant-based eating and gut health, while Dr. Mokadem explains why restrictive elimination diets and expensive supplements may not be the answer for everyone. Learn what the evidence supports, which warning signs deserve medical attention, and how a varied, balanced diet can help support digestive health.